منابع مشابه
On hedgehogs and human cancer
in vitro, specifically decreasing GLI1 messenger RNA (mRNA) levels, at concentrations ranging from 1 to 10mM showing dose-dependent effects, modulated by serum levels. The best tests for specificity rely on mimicry by targeting SMOH with RNA interference (RNAi), the use of insensitive SMOH mutants and pathway epistatic analyses. Targeting SMOH through lentivector-mediated short hairpin RNA (shR...
متن کاملPlane Lorentzian and Fuchsian hedgehogs
Parts of the Brunn-Minkowski theory can be extended to hedgehogs, which are envelopes of families of affine hyperplanes parametrized by their Gauss map. In [F], F. Fillastre introduced Fuchsian convex bodies, which are the closed convex sets of Lorentz-Minkowski space that are globally invariant under the action of a Fuchsian group. In this paper, we undertake a study of plane Lorentzian and Fu...
متن کاملDisclination Loops, Hedgehogs, and All That
Copyright and reuse: The Warwick Research Archive Portal (WRAP) makes the work of researchers of the University of Warwick available open access under the following conditions. Copyright © and all moral rights to the version of the paper presented here belong to the individual author(s) and/or other copyright owners. To the extent reasonable and practicable the material made available in WRAP h...
متن کاملResponses of foraging hedgehogs to badger odour
Enclosure and field trials were used to investigate the responses of hedgehogs, Erinaceus europaeus, to predator (badger,Meles meles) and non-predator odours. Two hypotheses were tested: (1) hedgehogs are capable of responding to badger odour; and (2) hedgehogs prefer not to forage in areas tainted with badger odour. In enclosure trials, hedgehogs almost exclusively avoided feeding at sites tai...
متن کاملHedgehogs tryst with the cell cycle.
Hedgehog proteins play an essential role during pattern formation in animal development and, increasingly, much of our appreciation of their modes of action is emanating from studies of their signalling mechanisms at the cellular level. Recent work has provided insights into how Hedgehog controls the cell cycle in a variety of circumstances. The data suggest that this influence may be direct an...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2002
ISSN: 1465-6906
DOI: 10.1186/gb-spotlight-20020904-01